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Advances in MS: Early Diagnosis of Multiple Sclerosis

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Peter Calabresi, MD
Fredrick Munschauer, MD
Patrick Parcells, MD

Traditionally, the diagnosis of multiple sclerosis (MS) required at least 2 different functional deficits occurring at 2 separate and distinct periods of time; it was a "diagnosis of exclusion," so all other possible causes had to be ruled out. Advances in the use of MRI have changed the algorithm for the diagnosis of MS, allowing for positive diagnosis and earlier treatment for the prevention of the disability that occurs early in the disease, even when MS is clinically silent.

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