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		Management of the Breakthrough Patient Sponsored by the Postgraduate Institute for Medicine Release date: January 2006 Expiration date: January 2007 Estimated time to complete activity: 1 hour This educational program is supported through an educational grant from Biogen IDEC and Elan Pharmaceuticals Inc. Differentiating perfect or near-perfect responders to platform therapy from those who are clearly non-responders poses no difficulty for clinicians. The lines between these categories and those who fall in between is an area of much difficulty, however. When to label a patient a suboptimal responder, a non-responder or one in transition to progressive disease and when to add or switch therapy is a difficult decision for most care providers, with no clear consensus even among MS specialists. Three MS specialists will give their opinions of the options for the less-than-optimal responder: when to consider a therapeutic change; whether and what to add as additional therapy, including various immunosuppressants as well as IV immunoglobulin; whether there is any role for switching among IFNs. Windows Me / XP / 2000. 800 MHz P3 processor. 256 MB RAM. Microsoft Internet Explorer (6.0 or higher). 16-bit sound card and Windows Media Player (9.0 or greater). Video Card capable of 16-bit color. Adobe Acrobat 6.0 or greater. Click here to review the complete CME information.
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